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BI 509/ MBB 602 GENOMICS                                                                                 (3L+0P) III

Objective
  To provide insight into the functional aspects of cell function by studying the genome as a whole with special emphasis on structural and functional genomics.

Theory

UNIT I
  Structural genomics: Classical ways of genome analysis, large fragment genomic libraries, physical mapping of  genomes, genome sequencing, sequence assembly and annotation, comparative genomics.

UNIT II
  Functional genomics: DNA chips and their use in transcriptome analysis, Mutants and RNAi in functional genomics, qPCR, SAGE, MPSS.

UNIT III
  Application of genomics in crop improvement, protein structure and function, proteins as enzymes, protein purification, 2D, mass spectrometry.

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